Dr Maija Kohonen-Corish
Senior Research Fellow; Group Leader, Cancer Research Program, Garvan Institute of Medical Research; Cancer Institute NSW Fellow; Conjoint Senior Lecturer, St Vincent’s Hospital Clinical School, The University of New South Wales; Visiting Scholar, University of Sydney
Email: m.corish 'at' garvan.org.au
Research Group: Lung and Colorectal Cancer
Education
2005 MHGSA Specialist Accreditation in Molecular Genetics, Human Genetics Society of Australasia
1988 PhD in Human Genetics, Australian National University, Canberra
1983 MSc University of Helsinki, Finland
1982 BSc University of Helsinki, Finland
Publications
Seng TJ, Currey N, Cooper WA, Lee C-S, Chan C, Horvath L, Sutherland RL, Kennedy C, McCaughan B and Kohonen-Corish M (2008). DLEC1 and MLH1 promoter methylation are associated with poor prognosis in non-small cell lung carcinoma. Br J Cancer 99: 375-382.
Ollila S, Sarantaus L, Kariola R, Chan P, Hampel H, Holinksi-Feder E, Macrae F, Kohonen-Corish M, Gerdes A-M, Peltomaki P, Mangold E, de la Chapelle A, Greenblatt M, Nystrom M. Pathogenicity of MSH2 missense mutations is typically associated with impaired repair capability of the mutated protein. Gastroenterology 2006; 131:1408-1417.
Kohonen-Corish MRJ, Cooper WA, Saab J, Thompson JF, Trent RJA, Millward MJ. Promoter hypermethylation of the O6-methylguanine DNA methyltransferase gene and microsatellite instability in metastatic melanoma. J Invest Dermatol 2006; 126:167-171.
Kohonen-Corish MR, Daniel JJ, Chan C, Lin BP, Kwun SY, Dent OF, Dhillon VS, Trent RJ, Chapuis PH, Bokey EL. Low microsatellite instability is associated with poor prognosis in stage C colon cancer. J Clin Oncol 2005; 23(10):2318-24.
Raevaara TE, Siitonen M, Lohi H, Hampel H, Lynch E, Lonnqvist KE, Holonski-Feder E, Sutter C, McKinnon W, Duraisamy S, Gerdes A, Peltomaki P, Kohonen-Corish MRJ, Mangold E, Macrae F, M G, de la Chapelle A, Nystrom M. Functional significance and clinical phenotype of nontruncating mismatch repair variants of MLH1. Gastroenterology 2005; 129(2):537-549.
van der Klift H, Wijnen J, Wagner A, Verkuilen P, Tops C, Otway R, Kohonen-Corish M, Vasen H, Oliani C, Barana D, Moller P, Delozier-Blanchet C, Hutter P, Foulkes W, Lynch H, Burn J, Moslein G, Fodde R. Molecular characterization of the spectrum of genomic deletions in the mismatch repair genes MSH2, MLH1, MSH6, and PMS2 responsible for hereditary nonpolyposis colorectal cancer (HNPCC). Genes Chromosomes Cancer 2005; 44(2):123-38.
Otway R, Tetlow N, Hornby J, Doe WF, Kohonen-Corish MRJ. Human gene mutations: MSH2 in hereditary nonpolyposis colorectal cancer. Human Genetics 2005; 118:546.
Kariola R, Otway R, Lönnqvist KE, Raevaara TE, Macrae F, Vos YJ, Kohonen-Corish M, Hofstra RMW, Nyström-Lahti M. Two mismatch repair gene mutations found in colon cancer patient - which one is pathogenic? Hum Genet 2003; 112:105-109.
Kohonen-Corish MRJ, Qin H, Daniel JJ, Cooper WA, Rivory L, McCaughan B, Millward MJ, Trent RJA. Lack of β-tubulin gene mutations in early stage lung cancer. Int J Cancer 2002; 101:398-399.
Kohonen-Corish MRJ, Daniel JJ, te Riele H, Buffinton GD, Dahlstrom JE. Susceptibility of Msh2 deficient mice to inflammation-associated colorectal dysplasia and cancer. Cancer Research 2002; 62:2092-2097.
MacKenzie JR, Mason SS, Hickford JGH, Kohonen-Corish MRJ, Bickerstaffe R. A polymorphic marker for the human cathepsin B gene. Molecular and Cellular Probes 2001; 15:235-237.
