Dr Paul Baldock
Senior Research Officer, Group leader, Bone Regulation Group, Bone and Mineral Research Program, Garvan Institute of Medical Research; RD Wright Research Fellow
Email: p.baldock 'at' garvan.org.au
Research Group: Bone Regulation
Education
2001 Ph.D., (Human Physiology), University of Adelaide
1994 B.Sc. (Hons 1), University of Adelaide.
Awards and Honours
2007-20011 RD Wright Fellowship, NHMRC
2007 Travel Award, Symposium Presentation, International Bone and Mineral Society
2006 Short-Term International Fellowship, International Human Frontier Science Program Organisation
2006 Travel Award, Frontiers of Skeletal Biology: International Bone and Mineral Society
2005 Young Investigator, Award Advances in Mineral Metabolism: American Society for Bone and Mineral Research
2004 Young Investigator Award, Anabolic Agents for the Treatment of Osteoporosis: American Society for Bone and Mineral Research
2003 Young Investigator Award, American Society for Bone and Mineral Research
2003 Travel Award, International Bone and Mineral Society
2002 Plenary Poster Award, American Society for Bone and Mineral Research
2001 Young Investigator Award, International Bone and Mineral Society
1996 AMRAD award, outstanding presentation, Australian Society for Medical Research.
1994 Campion Ma Ploust Award, most outstanding presentation, Australian Society for Medical Research.
1992 Outstanding poster, Australian Society for Medical Research, National Annual Scientific Meeting
Publications
Baldock PA, Allison SJ, Lundberg P, Lee NJ, Slack K, Lin EJD, Enriquez RF, McDonald MM, Zhang L, During MJ, Little DG, Eisman JA, Gardiner EM, Yulyaningsih E, Lin S, Sainsbury A, Herzog H. Novel role of Y1 Receptors in the Coordinated Regulation of Bone and Energy Homeostasis. J Biol Chem 2007 282:19092-19102. I.F. 5.9
Lundberg P, Allison SJ, Lee N, Baldock PA, Brouard N, Rost S, Enriquez R, Sainsbury A, Lamghari M, Simmons P, Eisman JA, Gardiner EM, Herzog H. Greater bone formation of Y2 knockout mice is associated with increased osteoprogenitor numbers and altered Y1-receptor expression. J Biol Chem 2007 282:19082-19091 I.F. 5.9
Sainsbury A, Lin S, McNamara K, Slack K, Eneriquez R, Lee N, Boey D, Smythe G, Schwarzer C, Baldock PA, Karl T, Lin EJ, Couzens M, Herzog H. Dynorphin knockout reduces fat mass and increases weight loss during fasting in mice. Molec Endo 2007 21:1722-1735.
Allison S, Baldock PA, Sainsbury A, Enriquez RF, Lee NJ, Lin EJD, Klugman M, During M, Eisman JA, Li M, Pan LC, Herzog H, Gardiner EM. Conditional deletion of hypothalamic Y2 receptors reverts gonadectomy-induced bone loss in adult mice. J Biol Chem 2006 281:23436-23444.
Baldock PA, Allison S, Mc Donald MM, Sainsbury A, Enriquez RF, Little DG, Eisman JA, Gardiner EM, Herzog H. Hypothalamic Regulation of Cortical Bone Mass: Opposing Activity of Y2 Receptor and Leptin Pathways. J Bone Miner Res 2006 21:1600-1607.
Baldock PA, Sainsbury A, Allison S, Lin D, Couzens M, Boey D, Enriquez, RF, Lin S, During M, Herzog H, Gardiner, EM. Hypothalamic control of bone formation: Distinct actions of leptin and Y2 receptor pathways. J Bone Miner Res 2005 20:1851-1857.
Baldock PA, Sainsbury A, Schwarzer C, Ueno N, Enriquez RF, Couzens M, Inui A, Herzog H, Gardiner EM. Synergistic Reduction in Adiposity and Increase in Bone Mass in Y2 / Y4 Receptor Double Knockout Mice. Mol Cell Biol 2003 23: 5225-5233.
Little DG, Peat R, McEvoy A, Williams P, Smith E, Baldock PA. Zolendroic acid treatment results in retention of femoral head structure after traumatic osteonecrosis in young wistar rats. J Bone Miner Res 2003 18:2016 –2022.
Baldock PA, Sainsbury A, Couzens M, Enriquez RF, Thomas GP, Gardiner EM, Herzog H. Hypothalamic Y2 receptors regulate bone formation. J Clin Invest 2002 109:915-921.
Gardiner EM, Baldock PA, Thomas GP, Sims NA, Henderson NK, Hollis B, White CP, Sunn KL, Morrison NA, Walsh WR, Eisman J. Increased formation and decreased resorption of bone in mice with elevated vitamin D receptor in mature cells of the osteoblastic lineage. FASEB J 2000 14:1908-1916.
