B Cell Immunobiology
Autoimmune diseases such as lupus, myasthenia gravis and hemolytic
anemia can arise when B cells produce rogue antibodies that attack the
body. Our investigations aim to identify the specific genes and
signalling pathways that regulate B cell survival, proliferation, and
differentiation; as well as the molecules and cells that drive antibody
production against foreign structures and prevent antibody responses
against ourselves. By understanding how B cells function we hope to
reveal new strategies for improving vaccines, controlling autoimmune
disease, and treating B cell malignancies.
Staff
Dr Dominique Gatto |
Tyani Chan |
Tahra Camidge |
Sandra Gardam |
News
B cell mutations that may cause cancers and autoimmune diseases
MEDIA RELEASE:
29 Feb 2008
To remain healthy, we must maintain exactly the right number of B cells, the white blood cells that produce antibodies. Scientists at Garvan have identified the factors critical to maintaining this important balance within our immune systems. When the balance fails, we become prone to developing certain cancers or autoimmune diseases.
Garvan student wins prestigious immunology award
17 Dec 2007
At its annual conference in early December, the Australasian Society of Immunology awarded Garvan PhD student, Sandra Gardam, its prestigious New Investigator Award. Sandra's research looks at B cells, the cells that produce antibodies. She has been investigating the mechanisms that ensure we have the right number of B cells in our bodies.
