B Cell Tolerance
Our ultimate goal is to prevent the immune system attacking the insulin producing beta cells of the pancreas, which leads to type 1 diabetes (T1D). Our research aims to identify the faulty mechanisms that allow the B cells that recognise beta cell proteins to persist and thus activate the destructive T cells. We also aim to identify novel genes that control the generation and function of this aberrant population of B cells, findings that could form the basis for new early stage therapies in T1D susceptible humans.
Staff
Jessica Stolp |
Lewis Cox |
