Campbell
People at high risk for the development of type 2 diabetes (i.e. normal glucose tolerant, healthy, first degree relatives of patients with type 2 diabetes) exhibit features of insulin resistance, whereas subjects without any family history of diabetes do not. Type 2 diabetes is a complex disease that is polygenic and subject to multiple environmental influences. By studying a carefully characterised population well before diabetes develops, it may be possible to unravel the complex array of factors that contribute to the condition.
Much of our work makes use of tissue biopsies to study the early changes in fat cells and in muscle that precede type 2 diabetes.
Staff
 Research OfficerDr Dorit Samocha Bonet |
 Clinical Research OfficerDr Alex Viardot |
 Clinical Research NurseLynne Schofield |
 PhD StudentLouise Purtell |
See also:
News
Simple diagnostic tool predicts Type 2 diabetes in South East Asians
MEDIA RELEASE:
07 Jul 2010
Researchers have estimated the prevalence of Type 2 diabetes in Vietnam, and have developed a simple tool for identifying individuals at high risk. In Ho Chi Minh City, a city of 6.4 million, the findings suggest that around 350,000 have diabetes, many of whom are unaware of the fact.
Better understanding of the all-consuming Prader-Willi Syndrome
MEDIA RELEASE:
12 May 2010
Garvan researchers have uncovered facts that take us a step closer towards understanding Prader-Willi Syndrome, a harrowing genetic disorder that causes insatiable appetite for life.
Weight gain when there’s a family history of Type 2 diabetes
MEDIA RELEASE:
11 May 2010
In the first study of its type, Garvan researchers have shown that healthy people with a genetic predisposition to Type 2 diabetes gain more weight overeating over the short term than their non-genetically-prone counterparts.
