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Garvan Institute

Sections
 

Bone Genetics and Epidemiology

 

Group Leader
Professor John Eisman AO

 
Group Leader
Dr Jackie Center

 
Group Leader
Professor Tuan Nguyen

 

Our research draws on the Dubbo Osteoporosis Epidemiology Study (DOES), which began in 1989 and is the world’s longest running large-scale epidemiological study of osteoporotic fractures in men and women.

We are using the DOES data to develop predictive models, based on multiple risk factors, to identify men and women at high risk of bone fractures and to determine who would benefit most from preventative interventions.

We are also continuing to search for new osteoporosis genes that may predict those who are at low risk of osteoporosis and bone fractures – taking into account environmental factors such as physical activity, dietary habits, medication, fall-related and hormonal factors.

Finding and understanding how these genes work and interact with other known genes will help identify targets for novel therapies.

Staff

Clinical Research Associate
Janet Watters
Clinical Research Associate
Shaye Field
Clinical Research Associate
Glenys Hubbard
nguyen_nguyen90.JPGResearch Officer
Dr Nguyen Nguyen
Dana BliucPhD Student
Dana Bliuc
Bich TranPhD Student
Bich Tran
Heather GordonResearch Assistant
Heather Gordon

News

 

Why measuring absolute risk of fracture could save many broken bones

MEDIA RELEASE: 28 Jul 2009
Garvan scientists stress the importance of measuring a person's absolute risk of fracture when determining their treatment options. Other factors currently determine whether or not the Australian Government will pay for preventative treatment.
 
 

Summarising a fractured debate about meat, fish, eggs, vegetables and bones

MEDIA RELEASE: 02 Jul 2009
Until now, medical opinion about the impact of vegetarian diets on bone health has been based on anecdotal evidence and a range of contradictory findings that sometimes rely on studies too small to be biologically relevant. A review and analysis of all relevant existing research shows that differences in bone mineral density between meat eaters and all vegetarians is 5%. The jury is still out on whether that translates into higher fracture risk.
 
 

Vegan Buddhist nuns have same bone density as non-vegetarians

MEDIA RELEASE: 16 Apr 2009
A study comparing the bone health of 105 post-menopausal vegan Buddhist nuns and 105 non-vegetarian women, matched in every other physical respect, has produced a surprising result. Their bone density was identical. The study was led by Garvan's Professor Nguyen in collaboration with a colleague in Vietnam.
 
 

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