Mucosal Autoimmunity
Cecile King's lab is interested mucosal autoimmunity. In type 1
diabetes (T1D), the insulin-producing beta cells of the pancreas are
destroyed by selftissue- destructive T cells. These cells express
markers that help us to determine, for example, their dependence upon
growth factors and where they have been in the body. We are
particularly interested in the relationship between the cells that
cause T1D and other autoimmune diseases that develop at the mucosal
interface between our bodies and the environment. Broad-based
suppression is commonly used to treat autoimmune diseases and
transplant recipients but it has an obvious drawback since we need a
functioning immune system in order to thrive. The aim of our research
is to identify target molecules for selective suppression of these
self-tissue-destructive cells.
Staff
| Postgraduate Student |
Postgraduate Student Alexis Vogelzang |
Nacer Boubenna |
