Genetic Cancer Risk Group

We are interested in the heritable aspects of cancer with a focus on two populations – the International Sarcoma Kindred Study (ISKS) and the Genetic Cancer Risk in the Young (RisC) study. Individuals with elevated cancer risk are increasingly being identified by genotype, especially in the absence of a family history. Our research includes the surveillance study in Multi-Organ Cancer prone syndromes (SMOC+), which screens genotypically identified individuals regularly and follows outcomes longitudinally.

We aim to further understand the genetic contribution to cancer risk and the implications of genotype identified risk. Potentially, this will more fully inform clinical surveillance strategies, treatment regimes, reproductive and lifestyle decisions, and possibly improve outcomes for families affected by cancer.