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Brooke Pereira

Dr Brooke Pereira

Role
Senior Research Officer
Lab/Group
Invasion and Metastasis Lab
Research Level
Senior Research Officer

Dr Brooke Pereira completed her PhD at Monash University under the supervision of Professor Gail Risbridger in early 2019. During her candidature she studied tumour-stroma interactions in prostate cancer using tissue engineering and quantitative proteomics. Brooke is now a Senior Post-doctoral Research Officer and Cancer Institute NSW Fellow in the Cancer Invasion & Metastasis Laboratory Group, headed by Professor Paul Timpson.

Dr. Pereira uses a range of cutting-edge approaches such as proteomics, genomics, patient-derived xenografts (PDX), spatial proteomics (mass spectrometry imaging), spatial transcriptomics and intravital (in vivo) imaging to investigate new and current anti-tumour agents in pancreatic cancer. Dr Pereira is a founding Executive member of the Australian Pancreatic Cancer Matrix Atlas (APMA; www.pancreaticcancer.net.au/apma/), a global resource for fibrotic-rich pancreatic cancer specimens within the Australian Pancreatic Cancer Genomic Initiative (APGI). She holds a Conjoint Lecturer position with UNSW since 2019 and currently supervises 3x PhD students: Katie Gordon (2023-, Tour de Cure Scholarship), Jessie Zhu (2022-, SPHERE UNSW Scholarship) & Antonia Cadell (2021-, PanCare Scholarship), with 1x PhD to completion (Shona Ritchie, 2020-24, International UNSW Scholarship).

Dr Pereira has published 31+ papers spanning cancer biology, proteomics and imaging and has been funded by National Tier funding bodies such as the National Health and Medical Research Council (NHMRC), Cancer Institute NSW, Cancer Council and Pankind. Her published work has resulted in several significant findings regarding (a) co-targeting strategies, (b) tumour microenvironment interactions, & (c) signalling networks during pancreatic cancer spread.

Awards

  • 2023NHMRC Ideas Grant – Chief Investigator A (CIA)
  • 2022Cancer Institute NSW Early Career Fellowship
  • 2022PanKind Accelerator New Treatment Grant - Co-Prinicipal Investigator
  • 2022Perpetual IMPACT Philanthropy Grant - Chief Investigator
  • 2022St. Vincent’s Clinic Foundation Grant - Chief Investigator
  • 2022UNSW Medicine Cancer Research Grant - Chief Investigator
  • 2020Sydney Catalyst Grant - Chief Investigator

Selected publications

See all publications
  • 2020
    The EMBO Journal10.15252/embj.2019104063

    Stromal cell diversity associated with immune evasion in human triple-negative breast cancer.

    Sunny Z Wu, Daniel L Roden, Chenfei Wang, Holly Holliday, Kate Harvey, Aurélie S Cazet, Kendelle J Murphy, Brooke Pereira, Ghamdan Al-Eryani, Nenad Bartonicek, Rui Hou, James R Torpy, Simon Junankar, Chia-Ling Chan, Chuan En Lam, Mun N Hui, Laurence Gluch, Jane Beith, Andrew Parker, Elizabeth Robbins, Davendra Segara, Cindy Mak, Caroline Cooper, Sanjay Warrier, Alistair Forrest, Joseph Powell, Sandra O'Toole, Thomas R Cox, Paul Timpson, Elgene Lim, X Shirley Liu, Alexander Swarbrick