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Helen Lenthall

Helen Lenthall

Role
Senior Research Assistant
Lab/Group
Antibody Therapeutics Lab

Selected publications

See all publications
  • 2025
    Proceedings of the National Academy of Sciences of the United States of America10.1073/pnas.2417544121

    Affinity maturation endows potent activity onto class 6 SARS-CoV-2 broadly neutralizing antibodies.

    Ohan Mazigi, David B Langley, Jake Y Henry, Deborah L Burnett, Meghna Sobti, Gregory J Walker, Romain Rouet, Harikrishnan Balachandran, Helen Lenthall, Jennifer Jackson, Stephanie Ubiparipovic, Peter Schofield, Simon H J Brown, Sebastian R Schulz, Markus Hoffmann, Stefan Pöhlmann, Jeffrey Post, Marianne Martinello, Golo Ahlenstiel, Anthony Kelleher, William D Rawlinson, Stuart G Turville, Rowena A Bull, Alastair G Stewart, Hans-Martin Jäck, Christopher C Goodnow, Daniel Christ
  • 2023
    Science Advances10.1126/sciadv.adf9063

    Monitoring AKT activity and targeting in live tissue and disease contexts using a real-time Akt-FRET biosensor mouse.

    James R W Conway, Sean C Warren, Young-Kyung Lee, Andrew T McCulloch, Astrid Magenau, Victoria Lee, Xanthe L Metcalf, Janett Stoehr, Katharina Haigh, Lea Abdulkhalek, Cristian S Guaman, Daniel A Reed, Kendelle J Murphy, Brooke A Pereira, Pauline Mélénec, Cecilia Chambers, Sharissa L Latham, Helen Lenthall, Elissa K Deenick, Yuanqing Ma, Tri Phan, Elgene Lim, Anthony M Joshua, Stacey Walters, Shane T Grey, Yan-Chuan Shi, Lei Zhang, Herbert Herzog, David R Croucher, Andy Philp, Colinda L G J Scheele, David Herrmann, Owen J Sansom, Jennifer P Morton, Antonella Papa, Jody J Haigh, Max Nobis, Paul Timpson
  • 2023
    The Journal of Experimental Medicine10.1084/jem.20221020

    Human PIK3R1 mutations disrupt lymphocyte differentiation to cause activated PI3Kδ syndrome 2.

    Tina Nguyen, Anthony Lau, Julia Bier, Kristen C Cooke, Helen Lenthall, Stephanie Ruiz-Diaz, Danielle T Avery, Henry Brigden, David Zahra, William A Sewell, Luke Droney, Satoshi Okada, Takaki Asano, Hassan Abolhassani, Zahra Chavoshzadeh, Roshini S Abraham, Nipunie Rajapakse, Eric W Klee, Joseph A Church, Andrew Williams, Melanie Wong, Christoph Burkhart, Gulbu Uzel, David R Croucher, David E James, Cindy S Ma, Robert Brink, Stuart G Tangye, Elissa K Deenick
  • 2023
    Nature Communications10.1038/s41467-023-36295-5

    Broadly neutralizing SARS-CoV-2 antibodies through epitope-based selection from convalescent patients.

    Romain Rouet, Jake Y Henry, Matt D Johansen, Meghna Sobti, Harikrishnan Balachandran, David B Langley, Gregory J Walker, Helen Lenthall, Jennifer Jackson, Stephanie Ubiparipovic, Ohan Mazigi, Peter Schofield, Deborah L Burnett, Simon H J Brown, Marianne Martinello, Bernard Hudson, Nicole Gilroy, Jeffrey J Post, Anthony Kelleher, Hans-Martin Jäck, Christopher C Goodnow, Stuart G Turville, William D Rawlinson, Rowena A Bull, Alastair G Stewart, Philip M Hansbro, Daniel Christ
  • 2022
    Nature Microbiology10.1038/s41564-022-01135-7

    Platform for isolation and characterization of SARS-CoV-2 variants enables rapid characterization of Omicron in Australia.

    Anupriya Aggarwal, Alberto Ospina Stella, Gregory Walker, Anouschka Akerman, Camille Esneau, Vanessa Milogiannakis, Deborah L Burnett, Samantha McAllery, Mariana Ruiz Silva, Yonghui Lu, Charles S P Foster, Fabienne Brilot, Aleha Pillay, Sabastiaan Van Hal, Vennila Mathivanan, Christina Fichter, Andrea Kindinger, Alexandra Carey Hoppe, Mee Ling Munier, Supavadee Amatayakul-Chantler, Nathan Roth, Germano Coppola, Geoff P Symonds, Peter Schofield, Jennifer Jackson, Helen Lenthall, Jake Y Henry, Ohan Mazigi, Hans-Martin Jäck, Miles P Davenport, David R Darley, Gail V Matthews, David S Khoury, Deborah Cromer, Christopher C Goodnow, Daniel Christ, Roselle Robosa, Damien J Starck, Nathan W Bartlett, William D Rawlinson, Anthony D Kelleher, Stuart G Turville