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Katherine Jackson

Dr Katherine Jackson

Role
Senior Research Officer
Lab/Group
Immunogenomics Lab

Dr Katherine Jackson completed her PhD at the University of New South Wales investigating the inference of antigen selection from immunoglobulin heavy chain sequence data. Her research focuses on the application of immune receptor repertoire sequencing methodologies to study both immune responses to vaccination and infection and to study the genetics of the immune gene loci, with an interest in the role of individual immunogenetic variability and its impact on the development of antibody repertoires and immune responses.

Following her PhD, Katherine has undertaken post-doctoral training at the University of New South Wales and Stanford University. During these roles she adapted methods developed during her doctoral studies to the larger immune receptor datasets that result from next generation sequencing platforms, and applied these to the monitoring B cell responses in vaccination and infection.

Katherine’s current research continues to focus on utilising immune receptor repertoire sequencing to understand the evolution of responses in contexts ranging from primary vaccination (e.g. Rabies vaccination) and infection (e.g. Ebola virus, acute EBV), to secondary vaccination (e.g. seasonal influenza vaccination) and circumstances of autoimmunity or immune dysregulation.

Awards

  • 2016Best Scientific Poster Prize (Stanford Pathology Retreat)
  • 2014Paper of the Month (BABS UNSW)
  • 2013ICI 2013 Bursaries to Young Immunologists
  • 2007ASI Travel Award
  • 2004Australian Postgraduate Award
  • 2004The Baldwin Shelston Waters Prize for best performance in Professional Issues in Biotech
  • 2003Faculty of Science Award for best performance in honours
  • 2003The Beckman Coulter prize for best performance in Honours in Bachelor of Science

Selected publications

See all publications
  • 2024
    The Journal of Experimental Medicine10.1084/jem.20231044

    Helper T cell immunity in humans with inherited CD4 deficiency.

    Antoine Guérin, Marcela Moncada-Vélez, Katherine Jackson, Masato Ogishi, Jérémie Rosain, Mathieu Mancini, David Langlais, Andrea Nunez, Samantha Webster, Jesse Goyette, Taushif Khan, Nico Marr, Danielle T Avery, Geetha Rao, Tim Waterboer, Birgitta Michels, Esmeralda Neves, Cátia Iracema Morais, Jonathan London, Stéphanie Mestrallet, Pierre Quartier Dit Maire, Bénédicte Neven, Franck Rapaport, Yoann Seeleuthner, Atar Lev, Amos J Simon, Jorge Montoya, Ortal Barel, Julio Gómez-Rodríguez, Julio C Orrego, Anne-Sophie L'Honneur, Camille Soudée, Jessica Rojas, Alejandra C Velez, Irini Sereti, Benjamin Terrier, Nancy Marin, Luis F García, Laurent Abel, Stéphanie Boisson-Dupuis, Joel Reis, Antonio Marinho, Andrea Lisco, Emilia Faria, Christopher C Goodnow, Julia Vasconcelos, Vivien Béziat, Cindy S Ma, Raz Somech, Jean-Laurent Casanova, Jacinta Bustamante, Jose Luis Franco, Stuart G Tangye
  • 2023
    Clinical Immunology (Orlando, Fla.)10.1016/j.clim.2023.109709

    Diversification and expansion of the EBV-reactive cytotoxic T lymphocyte repertoire following autologous haematopoietic stem cell transplant for multiple sclerosis.

    Jennifer Massey, Crisbel Artuz, Zoe Dyer, Katherine Jackson, Melissa Khoo, Malini Visweswaran, Barbara Withers, John Moore, David Ma, Ian Sutton
  • 2022
    Clinical Immunology (Orlando, Fla.)10.1016/j.clim.2022.109209

    Tracking the clonal dynamics of SARS-CoV-2-specific T cells in children and adults with mild/asymptomatic COVID-19.

    Weng Hua Khoo, Katherine Jackson, Chansavath Phetsouphanh, John J Zaunders, José Alquicira-Hernandez, Seyhan Yazar, Stephanie Ruiz-Diaz, Mandeep Singh, Rama Dhenni, Wunna Kyaw, Fiona Tea, Vera Merheb, Fiona X Z Lee, Rebecca Burrell, Annaleise Howard-Jones, Archana Koirala, Li Zhou, Aysen Yuksel, Daniel R Catchpoole, Catherine L Lai, Tennille L Vitagliano, Romain Rouet, Daniel Christ, Benjamin Tang, Nicholas P West, Shane George, John Gerrard, Peter I Croucher, Anthony D Kelleher, Christopher G Goodnow, Jonathan D Sprent, Joseph E Powell, Fabienne Brilot, Ralph Nanan, Peter S Hsu, Elissa K Deenick, Philip N Britton, Tri Giang Phan
  • 2022
    Frontiers in Immunology10.3389/fimmu.2022.1032911

    High titre neutralizing antibodies in response to SARS-CoV-2 infection require RBD-specific CD4 T cells that include proliferative memory cells.

    Chansavath Phetsouphanh, Weng Hua Khoo, Katherine Jackson, Vera Klemm, Annett Howe, Anupriya Aggarwal, Anouschka Akerman, Vanessa Milogiannakis, Alberto Ospina Stella, Romain Rouet, Peter Schofield, Megan L Faulks, Hannah Law, Thidarat Danwilai, Mitchell Starr, C Mee Ling Munier, Daniel Christ, Mandeep Singh, Peter I Croucher, Fabienne Brilot-Turville, Stuart Turville, Tri Giang Phan, Gregory J Dore, David Darley, Philip Cunningham, Gail V Matthews, Anthony D Kelleher, John J Zaunders
  • 2022
    Frontiers in Immunology10.3389/fimmu.2022.798300

    Haematopoietic Stem Cell Transplantation Results in Extensive Remodelling of the Clonal T Cell Repertoire in Multiple Sclerosis.

    Jennifer Massey, Katherine Jackson, Mandeep Singh, Brendan Hughes, Barbara Withers, Carole Ford, Melissa Khoo, Kevin Hendrawan, John Zaunders, Bénédicte Charmeteau-De Muylder, Rémi Cheynier, Fabio Luciani, David Ma, John Moore, Ian Sutton