Dr Qian Du
Dr Qian Du’s research focuses on understanding the influence of DNA replication timing on the genome and epigenome in breast and prostate cancer. Qian completed her Bachelor of Science (Hons) at the University of Melbourne, where she studied zebrafish models of colorectal cancer. Following her interests in epigenetics, Qian completed a PhD from University of New South Wales with Professor Sue Clark’s group in the Genomics and Epigenetics Division at the Garvan Institute of Medical Research, where she began her work on DNA replication timing and the cancer epigenome. In 2019, Qian received a National Health and Medical Research Council Investigator Grant Fellowship to continue her work.
Awards
- 2019NHMRC Investigator Grant - Emerging Leadership
- 2019UNSW Sydney Dean’s Award for Outstanding PhD Thesis
- 2018Student Award - Lorne Genome Conference
- 2017Best Oral Presentation - Australian Cell Cycle meeting 2017
- 2017Pathfinders Award
- 2017Young Investigator’s Award - AEpiA Epigenetics Conference
- 2015Best Student Presentation - Australian Bioinformatics and Computational Biology Society Conference (ABACBS)
- 2015Stuart Furler Travel Fund Award
Selected publications
See all publications- 2024Nature Structural & Molecular Biology10.1038/s41594-023-01181-7
The potential of epigenetic therapy to target the 3D epigenome in endocrine-resistant breast cancer.
- 2023Nature Cell Biology10.1038/s41556-022-01048-x
Quantifying propagation of DNA methylation and hydroxymethylation with iDEMS.
- 2021Clinical Epigenetics10.1186/s13148-021-01210-6
Identification of DNA methylation biomarkers with potential to predict response to neoadjuvant chemotherapy in triple-negative breast cancer.
- 2021Cell Reports10.1016/j.celrep.2021.109722
DNA methylation is required to maintain both DNA replication timing precision and 3D genome organization integrity.
- 2020Nature Communications10.1038/s41467-019-14098-x
Epigenetic reprogramming at estrogen-receptor binding sites alters 3D chromatin landscape in endocrine-resistant breast cancer.